Surgical treatment for heart failure: cell-based therapy with engineered tissue
نویسندگان
چکیده
منابع مشابه
Surgical Treatment for Heart Failure
ICM is defined as diffuse akinesis of the ventricle after myocardial ischemia, and the pathology is different from LV aneurysm, which is dyskinesis after myocardial infarction. The etiology has been described as chronic LV remodeling after the ischemia,1 and the surgical treatment of ICM was thought to be heart transplantation only. However, the new surgical procedure of endoventricular circula...
متن کاملRebuilding the Damaged Heart: Mesenchymal Stem Cells, Cell-Based Therapy, and Engineered Heart Tissue.
Mesenchymal stem cells (MSCs) are broadly distributed cells that retain postnatal capacity for self-renewal and multilineage differentiation. MSCs evade immune detection, secrete an array of anti-inflammatory and anti-fibrotic mediators, and very importantly activate resident precursors. These properties form the basis for the strategy of clinical application of cell-based therapeutics for infl...
متن کاملCell therapy for heart failure.
Correspondence: A. Terzic, MD, PhD, Mayo Clinic, 200, First Street SW, Rochester, MN 55905, United States E-mail: [email protected] The pandemic of ischemic heart disease is increasingly recognized as a leading cause of global morbidity. While modern treatment modalities for acute myocardial infarction have reduced early mortality, they have concurrently precipitated a higher incidence of c...
متن کاملSurgical treatment concepts for heart failure
Our present generation is seeing a continued increase in the incidence of heart failure worldwide. Fundamental advances in medical and surgical therapy for patients with heart failure has been laid out for over two decades, and a number of treatment options to prevent or delay its onset has, until now, been a main focus of experimental and clinical researches. Much as has been said and done, he...
متن کاملCell-Based Therapy of Ischemic Heart Failure
Ischemic heart failure (IHF), heart failure secondary to myocardial infarction, is the number one killer in the US. Despite all the major advances in cardiac interventions, its relevance is on the rise. There is an urgent need for an effective alternative therapy. Stem cells have the potential to ameliorate many chronic illnesses such as IHF. Like any new therapy, several unanswered questions n...
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ژورنال
عنوان ژورنال: Vessel Plus
سال: 2019
ISSN: 2574-1209
DOI: 10.20517/2574-1209.2019.16